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JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor
Mericitabine
In a rat PK study
12-tetrahydrogenio-1-hydroxy-13-methyl-14-(prop-1-en-2-yl)-4
Yamaguchi K
ARC 239 dihydrochloride 98198 JNJ-31020028 is a selective brainARC 239 dihydrochloride is a selective antagonist of 2B adrenoceptor with pKD value of 8. 8 . 2B adrenoceptor is a G protein coupled receptor. 2 adrenergic receptors include three subtypes: 2A, 2B and 2C, which play an important role in regulating neurotransmitter release from adrenergic neurons in the central nervous system and from sympathetic nerves. ARC 239 dihydrochloride is a selective 2B adrenoceptor antagonist. In rat brain, ARC 239 inhibited
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